Asante Kotoko will take on second placed Aduana Stars at the Baba Yara stadium on Wednesday as they look to return to winning ways to revive their title aspirations.
The Porcupine Warriors are without a win in their last five league games but secured a progression in the MTN FA Cup to round of 32 after beating second tier side Bekwai Youth Football Academy 3-1 on penalties.
Interim coach Frimpong Manso leads the team for the first time in the premiership on Wednesday.
He was at the dugout to steer affairs for the Fabulous side in Bekwai last Sunday.
Emmanuel Gyamfi is making a return into the team for midweek's fixture.
He was suspended for the cup match last weekend whilst shot stopper Felix Annan is ruled out with a shoulder injury.
Aduana Stars are still hopeful of topping the league table before the first round ends as they aim at upsetting Asante Kotoko SC on Wednesday.
Second tier outfit Eleven Wonders pipped the Fire Boys 1-0 to eject them from the FA Cup last Saturday.
Only a point are separating them and leaders WAFA SC.
They are turning all their attentions to winning the league this season. They have amassed eight points from away already.
A win or draw on Wednesday will improve that.
Influential right back and captain Godfred Saka is making a return from suspension for Wednesday's visit to Kumasi.
He was sent off against Great Olympics few weeks ago.
HEAD TO HEAD
Total league meetings = 14
Asante Kotoko SC wins = 4
Drawn matches = 5
Aduana Stars wins = 5
~ Asante Kotoko SC are without a win in their last five matches in the premier league.
(W0 D2 L3)
~ Aduana Stars have lost only one of their last six premier league fixtures.
(W2 D3 L1)
~ Asante Kotoko SC are unbeaten in their last sixteen home games in the premiership. They have drawn all of the last two.
(W10 D6 L0)
~ Aduana Stars have managed just one victory in their last five away games in the premier league.
(W1 D2 L2)
~ Asante Kotoko SC are unbeaten in their seven home premier league meetings with Aduana Stars.
(W4 D3 L0)
~ Aduana Stars have lost only once in their last five premier league matches against Asante Kotoko SC.
(W3 D1 L1)
~ Asante Kotoko SC have not conceded in any of their last five premier league fixtures at home.
~ Aduana Stars have managed to keep just one clean sheet in their six away games in the premiership this season.