New
- Presidential Spokesperson & Press Secretary to the President: Andrew Awuni
- Attorney General & Justice: Joe Ghartey
- Communication: Prof. Mike Ocquaye
- Education, Science & Sports: Papa Owusu Ankomah
- Energy: Joseph Adda
- Information & National Orientation: Kwamena Bartels
- Manpower, Dev?t & Employment: Boniface Saddique
- Aviation: Gloria Akuffo
- National Security: Francis Poku.
- Interior: Albert Kan Dapaah
- Local Gov?t, Rural Dev?t & Environment: Stephen Asamoah Boateng
Dismissed
- Joseph Boahene Aidoo: Western Regional Minister
- Nkrabeah Effah-Dartey: Deputy minister for the Interior
- Isaac Edumadze: Central Regional Minister
- Yaw Osafo Maafo, Minister of Education and Sports, has been dismissed. Infamous for the "419" loans a.k.a the IFC & Chinese barber loans when he was the finance minister
- Dr Kofi Konadu Apraku, Minister of Regional Integration and NEPAD and Member of Parliament (MP) for Offinso North has lost his position
- J Ayikoi Otoo Attorney-General and Minister for Justice - replaced by his deputy Joe Ghartey
- Dan Botwe, Information minister, has been relived of his post. The ex-General Secretary of the ruling party was not a favourite on the administration list, due to his opposition to Kufuor?s bid in the past when the NPP was in opposition.
- Christine Churcher, Environment and Science Minister, has been sacked
- Kwabena Agyepong, Press Secretary to the President.
- Dr. Gashika Agambilla: Deputy Minister for Environment and Science
- Moses Dani Baah: Deputy Minister for Private Sector Development
- Kofi Osei Ameyaw: Deputy Minister for Trade and Industry
- J H Mensah: Senior Minister
"Recycled"
- Ms Gloria Akuffo: From ? to Minister of State for Aviation:
- Theresa Tagoe: From Deputy Minister of Lands Forestry and Mines to Deputy Greater Accra Regional minister
- Minister of State for Culture and Chieftaincy: Mr Sampson K. Boafo
- Office of the President: Charles Bintim, Mr K. Adjei Darko and Ms Elizabeth Ohene.
- Elizabeth Ohene: Moves to office of the presidency from Minister of State in charge of Tertiary Education:
- Sampson Kwaku Boafo: Moves from Ashanti Regional Minister to Minister of state for Culture and Chieftaincy
- Charles Bintim: Minister of local Government and Rural Development, who deposited a whopping ?1.95 billion in his personal bank account with the High Street Branch of Barclays Bank within a period of eight months. Moves to office of the presidency
No Change
- Defence: Dr. Kwame Addo Kufuor
- Foreign Affairs, Regional Integration & NEPAD: Nana Akuffo Addo
- Finance & Economic Planning: Kwadwo Baah Wiredu
- Food & Agriculture: Ernest Debrah
- Health: Maj (Rtd) Courage Quashigah
- Lands, Forestry & Mines: Prof. Dominic Fobih
- Tourism & Diasporean Relations: Jake Obetsebi Lamptey
- Parliamentary Affairs: Felix Owusu Adjepong
- Public Sector Reform: Dr. P. Kwesi Ndoum
- Trade, Industry, Private Sector & PSI: Allan Kyeremanteng
- Transportation: Dr. Richard Anane
- Water Resources, Works & Housing: Hackman Owusu Agyeman
- Fisheries: Gladys Asmah
- Women & Children?s Affairs: Hajia Alima Mahama
- Ports & Railways: Prof. C. Ameyaw Akumfi
- Mr. Kwadwo Mpiani, Chief of Staff and Minister of Presidential Affairs
Regional Ministers
- Ashanti: Mr E.A. Owusu-Ansah
- Brong Ahafo: Mr I. Baffour Awuah
- Central: Nana Ato Arthur
- Eastern: Mr Yaw Barimah
- Greater Accra: Sheik I.C. Quaye
- Northern: Alhaji Mustapha Ali Idris
- Upper East: Mr Boniface Agambila
- Upper West: Mr Ambrose Derry
- Volta: Kofi Dzamesi
- Western Mr A. Evans Amoah
Deputy Regional Ministers
- Ashanti, Mr L. Akwasi Prempeh
- Brong Ahafo, Mr A. Kwadwo Kwakye
- Eastern Ms Suzie Mensah
- Greater Accra, Ms Theresa A. Tagoe
- Northern: Mr Issah Ketekewu
- Upper East Mr A. Awudu Yeremiah
- Upper West, Mr George Hikah Benson
- Volta: Mr Joseph Kwaku Nyan.
Deputy Ministers
- Office of the President: Mrs M. Bampoe Addo
- Attorney General and Justice: Mr K. Osei Prempeh
- Communication: Dr Aggrey Ntim
- Defence: William Ofori Boafo
- Education, Science and Sports: Mr K. Amporfo Twumasi, Mr O.B. Amoah and Mrs A. Baiden Amissah
- Energy: Mr K. T. Hammond
- Finance and Economic Planning: A. A. Osei, Dr Y. Djan-Baffour
- Fisheries: Mr Daniel Dugan
- Food and Agriculture: Mr Clement Eledi and Ms Anna Nyamekye
- Foreign Affairs, Regional Integration and NEPAD: Mr A. Osei-Adjei and Shirley Ayorkor Botchewey
- Health: Dr Gladys Norley Ashitey and Mr S. Owusu-Agyei
- Information and National Orientation: Mrs Oboshie Sai-Cofie
- Interior: Mr Agyeman Manu
- Lands, Forestry and Mines: Mr A. Adjei-Yeboah and Ms Rita Tanliddi
- Local Government, Rural Development and Environment: Mr Kofi Poku Adusei and Mr A. Dwuma Odoom
- Manpower Development, Youth and Employment: Mrs A. F. Osei-Opare and Dr C.Y. Brempong-Yeboah
- Tourism and Diaspora Relations: Mr Joe Baidoe-Ansah
- Trade, Industry and Private Sector and PSI: Gifty Ohene-Konadu and Mr K. Asiedu Afram
- Water Resources, Works and Housing: Ms Cecilia A. Dapaah and Mr Christopher Addae
- Port and Railways: Ms Sophia Horner-Sam.