Ghana could face Nigeria in the round of 16 at this year’s Africa Cup of Nations.

The Black Stars are on the verge of renewing a rivalry with their nemesis after the Super Eagles failed to top Group B following a 2-0 defeat at the hands of debutants Madagascar.

A second-place finish for Ghana in Group F will set up the epic clash between the two teams.

Ghana, currently locked with 2points in the Group will take on Guinea Bissau in the final Group match on Tuesday with Cameroon who are top of the table with 4points also facing Benin in the other Group match.

A win for Ghana over Guinea Bissau and a victory for Cameroon over Benin will see the two powerhouses grabbing the two available slots in the Group with the Black Stars finishing runners up behind the defending Champions (Cameroon) hence facing Nigeria in the last 16.

Ghana last played Nigeria at the semi-finals of the 2010 Africa Cup of Nations tournament in Angola, a game the Black Stars won 1-0 courtesy an Asamoah Gyan header.