Fire has gutted the Yegoala hotel at Ahodwo, a suburb of Kumasi in the Ashanti region.
It is unclear what sparked the fire which has destroyed several items in the hotel, Friday.
Personnel of the fire service are currently at the scene trying to put out the flame.
The Yegoala hotel belongs to the former Ghana International Anthony Yeboah. He has another branch of the hotel in Accra, Ghana’s capital.