Black Meteors captain, Daniel Afriyie Barnieh, midfielder Emmanuel Essiam, and Sylvester Simba have been benched as Ibrahim Tanko named his lineup to face Morocco.
Emmanuel Yeboah, Salim Adams, and Hafiz Ibrahim replace the trio respectively in the starting eleven.
Danlad Ibrahim maintained his place in goal, behind a backline of Aaron Essel, Terry Yegbe, David Oppong Afrane, and Edmund Arko-Mensah.
Salim Adams, Hafiz Ibrahim, and Dominic Nsobila complete the midfield trio while Fatawu Isshaku, Ernest Nuamah, and Yeboah lead the attacking line.
Ghana and Morocco are tied on the same point in the group after they both won their opening game. A win for either side will send them to the semi-finals with a game to spare.
The game is set at 20:00 GMT kickoff time at the Prince Moulay Abdellah Stadium.
Full line-up below
Danlad Ibrahim (GK) (C)
Aaron Essel
Terry Yegbe
David Oppong Afranie
Edmund Arko-Mensah
Dominic Nsobila
Salim Adams
Hafiz Ibrahim
Abdul Fatawu Issahaku
Ernest Nuamah Appiah
Emmanuel Yeboah