Champion club Kumasi Asante Kotoko will host Istanbul FC while New Edubiase play Fetteh Feyenoord for the next round of the competition
The clash of the pairings should be Okwawu United against defending champions, Medeama SC.
The Round of 16 stage is however hit by outstanding fixtures due to prolonged disciplinary issues.
Two fixtures in the Round of 16 stage remain uncertain due to this setback.
Below is the full Round of 16 Fixtures after the draw at the GFA conference room on Thursday.
Asante Kotoko vrs Istanbul FC
Berekum Chelsea vrs Inter Allies
Hasaacas vrs Gold Stars
Fetteh Feyenoord vrs New Edubiase
AshantiGold vrs Mighty Jets
Rospack/Right to Dream/Ho Dynamos/ King Faisal vrs Metro Stars
Okwawu United vrs Medeama
Aduana Stars/Asokwa Deportivo/Dunkwa United/Dawenya United/Royal Faith FC/ Bazooka vrs Bechem United.
The Round of 16 fixtures will be cleared between 20-23 February.
Meanwhile, some clubs have been fined for causing violence and not cooperating for TV coverage.
According to Kurtz Okraku, a member of the FA Cup Committee, three teams , including Medeama, Bibiani Gold Star have been fined 1,500 ghc for indiscipline.