Medeama return to domestic duties with an outstanding Ghana Premier League against Ebusua Dwarfs on Wednesday.
The Tarkwa-based side are smarting from their 2-1 aggregate win over Libyan side Al Ittihad in the CAF Confederation Cup on Sunday.
The two-time FA Cup champions have struggled so far in the domestic top-flight as they bottom of the table with a single point from three games.
The Mauve and Yellows last lost 2-0 at home to Hearts of Oak and will be keen to rewrite the wrong.
They host fellow strugglers Ebusua Dwarfs at the Tarkwa and Aboso Park eager to bag their first three points of the season.