District Results of Presidential Elections 2000 for Akwapim South
| Candidate | Votes | Percentage (%) |
| Mills | 17664 | 42.1 |
| Kuffuor | 22898 | 54.6 |
| Goosie | 277 | 0.7 |
| Hagan | 351 | 0.8 |
| Mahama | 204 | 0.5 |
| Wereko Brobby | 118 | 0.3 |
| Lartey | 402 | 1 |
| Valid | 0 | 0 |
| Rejected | 0 | 0 |
| Total Turnout | 0 | 0 |
| Registered | 0 |